RSV, Virus RSV, Virus

RSV Diagnosis, Prevention, and Management

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Testing for RSV is key for diagnosis1,2

RSV, Patient

Diagnosis in primary care is usually based on symptoms and local epidemiology3
RSV is under-diagnosed and under-reported in adults, in part because:

  • Symptoms of RSV may be indistinguishable from those of other respiratory infections2
  • Laboratory diagnosis of viral respiratory infections in adults is not routine practice4

Different laboratory tests are available to confirm RSV infection:1,2

RSV, PCR, Testing

RNA detection by RT-PCR1,2

  • Excellent sensitivity and specificity
  • Useful for older children and adults with lower viral loads in respiratory secretions
RSV, Antigen, Testing

Antigen detection by ELISA or immunofluorescence1,2

  • Most reliable in young children in whom these tests have sensitivity of around 80–90%
  • Less useful in older children and adults due to low viral loads
RSV, Testing

Culture isolation1,2

  • Time consuming (2–5 days) and requires skilled personnel
  • Generally reliable in young children
  • Less useful in older children and adults (due to lower viral loads)

Early diagnosis may help provide better care for older adults with RSV4

Diagnosis of RSV in adults may help to:

RSV, Patient

Enable timely isolation of infected patients in acute care settings4

RSV, Stopwatch

Inform clinical decisions and enable implementation of early interventions*4,5

RSV, Pharmacy

Improve counseling of patients and their families about prognosis and need for post-hospitalization rehabilitation services4

RSV, Pharmacy

Reduce inappropriate use of antibiotics4,5

*For example, chest physiotherapy, bronchodilators, anti-inflammatory treatments, physical therapy5

There is currently no vaccine available to protect against RSV6

For adults, infection prevention and control measures remain the best protection against RSV. Prevention measures can help reduce the risk of RSV transmission to vulnerable populations at risk of severe RSV disease.6

RSV, Cough

Cover your coughs and sneezes with a tissue or your upper shirt sleeve, not your hands6

RSV, Hygeine

Wash your hands often with soap and water for at least 20 seconds6

RSV, Distance

Avoid close contact with individuals infected with RSV6

RSV, Hygiene

Clean frequently touched surfaces such as door knobs and mobile devices6

Currently no specific treatments for RSV are available for adults6,7

RSV, Virus

Supportive care is the basis of therapy for acute RSV infection in adults, and may include bronchodilators, supplemental oxygen, fluid replacement and antipyretics8

Learn more about RSV disease and its burden in adults:

RSV, Virus

RSV Disease Overview

RSV is a contagious respiratory virus that can lead to serious complications

LEARN MORE

RSV, Virus

Risk Factors and Clinical Burden of RSV in Older Adults

Older adults and adults with underlying conditions are at increased risk of severe illness due to RSV infection

LEARN MORE

RSV, Virus

RSV Diagnosis, Prevention, & Management

Testing for RSV is key for diagnosis. There currently is no specific treatment or prevention for RSV disease in adults

LEARN MORE

Abbreviations

ELISA, enzyme-linked immunosorbent assay; LRTI, lower respiratory tract infection; PCR, Polymerase chain reaction; RT-PCR, reverse transcription PCR; RSV, respiratory syncytial virus

References

  1. Henrickson KJ, Hall CB. Pediatr Infect Dis J 2007;26:S36–S40
  2. CDC, 2020. RSV – Information for healthcare professionals. https://www.cdc.gov/rsv/clinical/index.html Accessed August 2022
  3. Mayo Clinic, 2021. RSV diagnosis and treatment. https://www.mayoclinic.org/diseases-conditions/respiratory-syncytial-virus/diagnosis-treatment/drc-20353104?p=1 Accessed August 2022
  4. Branche AR, Falsey AR. Drugs Aging 2015;32:261–269
  5. Lee N et al. J Infect Dis 2019;220:969–979
  6. CDC. RSV – Prevention. https://www.cdc.gov/rsv/about/prevention.html Accessed August 2022
  7. National Foundation for Infectious Diseases (NFID), 2016. RSV in older adults. https://www.nfid.org/wp-content/uploads/2019/08/rsv-report.pdf. Accessed August 2022. 
  8. Nam HH, Ison MG. BMJ 2019;366:l5021

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NX-GBL-RSA-WCNT-220004 | January 2023