Image of adjuvant

Vaccinology

Vaccines are biological products that induce an immune response and confer protection against infection or disease using a variety of technologies and platforms.1

Vaccination is a key component of preventative healthcare, saving millions of lives from infectious disease every year.2

The potential role of vaccination is expanding beyond infectious diseases to conditions including cancer, allergies and autoimmune diseases.3

Vaccine technologies

Image of adjuvant

The history of vaccines

Immunisation has a long history as a key component of preventative healthcare1,2,4,5

LEARN MORE

Image of mRNA

Different types of vaccine

Vaccines induce active immunity through a growing range of different mechanisms1,6

LEARN MORE

Image of an immune cell

What is an adjuvanted vaccine?

Adjuvants are a diverse group of substances used to enhance the immune response to a vaccine1,7

learn MORE

Image of adjuvant

The expanding role of vaccines

With new opportunities in combatting non-infectious disease, and increasing importance in the fight against antimicrobial resistance, the potential of vaccines is expanding2,3

LEARN MORE

Supporting patients with decisions about vaccination

Image of mRNA

What influences decisions about vaccination?

While most people accept vaccination in the majority of populations globally, a range of factors can act as barriers that delay or prevent uptake8,9

LEARN MORE

Image of DNA

Discussing vaccines with patients

As trusted advisers about vaccination, healthcare workers have a key role in discussions about vaccines9-11

LEARN MORE

References

  1. Pollard AJ and Bijker EM. A guide to vaccinology: From basic principles to new developments. Nat Rev Immunol 2021;21:83–100.
  2. World Health Organization. Vaccines and immunization. https://www.who.int/health-topics/vaccines-and-immunization (accessed February 2024).
  3. PhRMA. Medicines in Development for Vaccines 2020 Report. https://phrma.org/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/PDF/medicines-in-development-for-vaccines-2020.pdf (accessed February 2024).
  4. World Health Organization. A brief history of vaccines. https://www.who.int/news-room/spotlight/history-of-vaccination/a-brief-history-of-vaccination (accessed February 2024).
  5. Plotkin S. History of vaccination. Proc Natl Acad Sci USA 2014;111:12283–12287.
  6. Vetter V et al. Understanding modern-day vaccines: What you need to know. Ann Med 2018;50:110120.
  7. Verma SK et al. New-age vaccine adjuvants, their development, and future perspective. Front Immunol 2023;14:1043109.
  8. MacDonald NE. Vaccine hesitancy: Definition, scope and determinants. Vaccine 2015;33:4161–4164.
  9. World Health Organization. Ten threats to global health in 2019. https://www.who.int/news-room/spotlight/ten-threats-to-global-health-in-2019 (accessed February 2024).
  10. Nuwarda RF et al. Vaccine hesitancy: Contemporary issues and historical background. Vaccines (Basel) 2022;10:1595.
  11. The Lancet Child & Adolescent Health. Vaccine hesitancy: A generation at risk. Lancet Child Adolesc Health 2019;3:281.

Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/. Adverse events should also be reported to GlaxoSmithKline on 0800 221 441.

©2024 GSK group of companies. All rights reserved.

June 2024 | NP-GB-HZU-WCNT-240023 (V1.0)